Subtilis Bacillus

JÖRG STÜLKEINSTITUT FÜR MIKROBIOLOGIE UND GENETIK, UNIVERSITÄT GÖTTINGENThe hay bacillus Bacillus subtilis has attracted scientifi c interest formore than 100 years due to its ability to form heat-stable spores as anexample of a rather simple differentiating organism. Thus, this bacterium became one of most studied model organisms. Moreover, B. subtilis is used in many biotechnological …

Bacillus subtilis – Topmodel für Forschung, Gesundheit und Biotechnologie Read More »

Examining the Gastrointestinal and Immunomodulatory Effects of the Novel Probiotic Probiotics make up a large and growing segment of the commercial market of dietary supplements and are touted as offering a variety of human health benefits. Some of the purported positive impacts of probiotics include, but are not limited to, stabilization of the gut microbiota, …

Bacillus subtilis DE111 Read More »

on Intestinal Barrier Function and Inflammatory Response Strong tight junctions and curtailed inflammatory responses under stressful conditions are key for optimal digestive health. Bacillus-based probiotics are increasingly being used to maintain broilers’ health, but their mode of action is often not well-defined. In the present study we used Caco-2 cells as a model for intestinal epithelia …

Effect of Bacillus subtilis Strains Read More »

Protects against a-Synuclein Aggregation in C. elegans Recent discoveries have implicated the gut microbiome in the progression and severity of Parkinson’s disease; however, how gut bacteria affect such neurodegenerative disorders remains unclear. Here, we report that the Bacillus subtilis probiotic strain PXN21 inhibits α-synuclein aggregation and clears preformed aggregates in an established Caenorhabditis elegans strains trigger the protective effect via both spores and vegetative cells, partly due to …

Probiotic Bacillus subtilis Protects against Read More »